In a seemingly quiet town a mysterious meteor shower produces a sinister green meteorite that seems to have a dangerous effect on the dogs that who once were the kind well-behaved dogs we once knew turn into vicious killers and the residents are forced to engage in a battle of man vs beast as man's best friend turns into their worst enemy and one teenage girl named Roslyn has to fight her way through the vicious canines accompanied by her faithful dog shemp they must find a way to survive against the dogs they once called man's best friend 宁静的夜晚，一阵突来的陨石雨袭卷天空，坠落四处的绿色陨石散发着一股神秘能量，让原本乖巧的狗儿们变得异常暴躁，甚至像有目的似地开始组织，疯狂攻击人类。在小镇陷入混乱之际，萝丝琳与她尚未变异的小狗夏普幸运逃过野狗攻击，但她们得赶在沦陷之前，尽快与家人会合，逃出这个狂犬肆虐的人间炼狱
