In New Orleans, Madison Walker suffers from dissociative identity disorder (DID) and tries to commit suicide. She is treated together with other patients by the psychologist Dr. Elizabeth Barnes. Madison has an estranged mother, who is a religious fanatic woman, and her father was neglectful with her when she was younger. When Madison leaves the psychiatric hospital, she goes to her old apartment. Then she decides to lock herself in the apartment for thirty day expecting to find why she is so messed up since she has neither friend not a job. On the 30th day, Madison makes an important discovery about Dr. Barnes and her patients. 我擦，这是个什么片子。每个人都是一座孤岛。 A woman suffering from multiple personality disorder tries to piece back together her life.
