In this story, Horton discovers there is a microscopic community of intelligent beings called the Who's living on a plant that only he can hear. Recognising the dangers they face, he resolves to keep them safe. However, the other animals around him think Horton has gone crazy thinking that there are such beings. They resolve to take action for his own good and Horton and The Who must struggle against these impossible odds to prevent a tragedy. 不是我们选择了那最好的，是那最好的选择了我们。胡思乱想。A person。A person is a person, no matter how small!。 霍顿（金·凯瑞 Jim Carrey 配音）是一头大象，无忧无虑的生活在丛林里面，每天都很快乐。但是，突然有一天，它的一个惊人发现彻底改变了它的生活。它发现，在一粒浮尘上有细微的声音传出来，经过仔细辨认，原来在浮尘上有一个“无名镇”因一颗果实的撞击而脱离的原来的地方，进而被一颗苜蓿花粉带着到处游荡。“无名镇”上的居民急切希望能有一个稳定的地方继续生活，进而向外界发出了求救信号。但是，虽然霍顿对这一切深信不已，当它将自己知道的一切告诉身边的朋友时，却发现没有一个人相信它，反而认为它疯了。为了拯救“无名镇”霍顿备受大家的嘲笑，顶着“幻想症患者”的恶名，不顾一切的想将“无名镇”送回到属于他们的世界里。
