Small-town accountant Frank Bigelow goes to San Francisco for a week's fun prior to settling down with fiancée Paula. After a night on the town, he wakes up with more than just a hangover; doctors tell him he's been given a "luminous toxin" with no antidote and has, at most, a week to live! Not knowing who did it or why, Bigelow embarks on a frantic odyssey to find his own murderer. 小城镇会计Frank Bigelow前往旧金山一周的乐趣，然后安定下来与未婚妻保拉。在城里过夜后，他醒来时不仅仅是宿醉；医生告诉他，他被给予了一种没有解毒剂的“发光毒素”，最多只能活一个星期！不知道是谁干的，也不知道为什么，毕格罗开始疯狂的冒险寻找自己的凶手。
