Old St. Leopold's Hospital has many urban legends surrounding it, but the residents of Bridgeport all agree on one thing: tortured souls roam its abandoned halls. The mystery proves too much for a pretty young student who decides to investigate for her senior class project. Unfortunately, she does not find ghosts. She, instead, finds Stanley... serial rapist, murderer, and psychopath. As the young girl becomes Stanley's new pet, a team of young investigators descend on the hospital to "hunt some ghosts." Stanley sees nothing but fun and games in his future. But, what Stanley does not know is that the hospital truly is haunted and the restless spirits there are not happy with what he has been doing. 舊聖利奧波德醫院周遭有許多靈異的傳聞，這裡的居民深信這間醫院受到了詛咒，而不敢靠近。一天，一位女大生為了研究論文來到這間醫院，卻也在不久後就消失不見。一群不信邪的辣妹參加了電視台的靈異節目，要到這間醫院住上一晚，但她們發現的不是鬼，而是躲藏在醫院的變態殺人魔們。前所未有的可怕殺戮即將襲來，究竟誰能活著走出醫院大門？
